- Although children of all ages may develop COVID-19, infants are especially susceptible to severe disease, as are children with comorbid respiratory or immunocompromising conditions.
- Editorial notes the "major role" of children in community-based transmission.
Why this matters
- WHO offers technical guidance on home care.
- Clinicians should ensure parents/caregivers are counseled on isolating children with mild symptoms from the rest of the household.
- 2143 children.
- Median age 7 (interquartile range, 2-13) years.
- 56.6% (1213) boys.
- 34.1% (731) laboratory-confirmed COVID-19; 65.9% (1412) suspected disease.
- 4.4% (94) asymptomatic.
- 50.9% (1091) mild.
- 38.8% (831) moderate severity.
- Severe, critical case rates by age group:
- 1-5 years: 7.3%.
- 6-10 years: 4.2%.
- 11-15 years: 4.1%.
- ≥16 years: 3.0%.
- Median time from illness onset to diagnosis: 2 (range, 0-42) days.
- Most cases diagnosed 1 week after illness onset.
- Most pediatric cases in China concentrated in Hubei province, surrounding areas.
- Nationwide cohort assessing epidemiology, transmission patterns of pediatric patients with COVID-19 reported to Chinese CDC from January 16 to February 8, 2020.
- Funding: Science and Technology Commission of Shanghai Municipality.
- Temporal data on clinical characteristics lacking.
- Some missing confounders (e.g., exposure history, related incubation period).
- Ongoing cases.