- In comparing children classified as hypertensive under the 2017 guidelines update to the 2004 definitions, the 2017 guidelines capture children who have increased risk for adult disease.
- This long-term study finds better sensitivity in the 2017 classifications for those at risk for later adult metabolic syndrome, hypertension, and left ventricular hypertrophy (LVH).
Why this matters
- Accurately identifying children at higher risk can open the way to early lifestyle interventions to reduce that risk.
- 2017 guidelines classified more children as having stage I or II hypertension vs 2004 version that categorized them as having prehypertension.
- Proportions of children captured by the 2004 vs 2017 guidelines who later went on to develop specific conditions were higher (e.g., 12% vs 19% for LVH).
- ORs (95% CIs) were higher with hypertension diagnosed by 2017 vs 2004 guidelines:
- Adult hypertension: 2.37 (1.67-3.35);
- Metabolic syndrome: 1.50 (1.07-2.31); and
- LVH: 2.18 (1.23-3.88).
- Longitudinal, multicenter Bogalusa Heart Study, Louisiana.
- 3940 children (age, 3-18 years; 47% boys); 36-year follow-up from childhood.
- Funding: NIH.
- Community-based sample, and generalizability is not clear.