Pediatric opioid exposures declining, but morbidity remains high

  • Patel AM & al.
  • J Pediatr
  • 4 Jan 2019

  • curated by Kelli Whitlock Burton
  • Clinical Essentials
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • 61% of pediatric exposures to opioids between 2010 and 2014 occurred in children aged 5 years or younger; half of all exposures resulted in a visit to a healthcare facility, and 7% resulted in a serious outcome.

Why this matters

  • Although overall pediatric opioid exposures decreased during the study period, more preventive and education efforts are needed, specifically targeted by age group and type of opioid.

Study design

  • This retrospective, cross-sectional study used the National Poison Data System between January 2010 and December 2014 to evaluate 83,418 opioid exposures in children aged
  • Funding: None disclosed.

Key results

  • 5-year prevalence rates of opioid exposures and poisoning were 22.6 and 11.8 per 100,000 children, respectively.
  • Between 2010 and 2014, mean number of pediatric opioid exposures decreased from 28 to 22 per 100,000 children (P<.0001>
  • 61.1% exposures were among children aged ≤5 years, 73.4% were unintentional, and >90% occurred at home.
  • Nearly one-half of exposures were treated in an emergency department or were admitted for care.
  • Of 64,045 cases with 1 opioid product exposure from single/combination opioid, 7% had a serious outcome.

Limitations

  • Risk for bias.
  • Number of exposures may be underestimated.

Coauthored with Antara Ghosh, PhD

Please confirm your acceptance

To gain full access to GPnotebook please confirm:

By submitting here you confirm that you have accepted Terms of Use and Privacy Policy of GPnotebook.

Submit