Pediatric PFMT relieves drug-resistant overactive bladder

  • Pekbay Y & al.
  • Neurourol Urodyn
  • 20 Apr 2019

  • International Clinical Digest
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Takeaway

  • Biofeedback-assisted pelvic floor muscle therapy (PFMT) improves symptoms and increases functional bladder capacity in children with drug-resistant overactive bladder (OAB).
  • The therapy is effective in children with or without dysfunctional voiding with secondary bladder overactivity (DV/SBO).

Why this matters

  • Antimuscarinics such as oxybutynin are a first-line treatment for OAB, but do not always work and can cause adverse effects that are more pronounced in children than in adults.

Study design

  • Researchers analyzed the health records of children with drug-resistant OAB, either with or without DV/SBO, who were treated with PFMT (N=24; 66.6% boys; mean age, 8.1±2.0 years; age range, 6‐13 years).
  • Funding: None disclosed.

Key results

  • In patients with DV/SBO:
    • Urgency was improved or cured in 6 of 7 (86%; P=.031).
    • Maximum voided volume (maxVV) increased from 115.6 to 175.7 mL (P=.063).
  • In patients without DV/SBO:
    • Urgency was improved or cured in 12 of 17 (71%; P<.0001>
    • MaxVV increased from 81.6 to 150.9 mL (P<.0001>

Limitations

  • The study was retrospective and had a small sample size; ethical considerations precluded establishing an untreated control group.

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