- Overnight oximetry for children with sleep-disordered breathing (SDB) can predict ability of adenotonsillectomy (T/A) to resolve hypoxemia.
Why this matters
- For evaluating children with SDB, oximetry is cheaper, easier, and more widely available than gold-standard polysomnography.
- CHANIA: prospective randomized controlled single-blind parallel-group trial.
- Participants: 140 children aged 4-10 years with snoring, adenotonsillar hypertrophy.
- All were T/A candidates at a Greek regional hospital.
- Participants randomly assigned to overnight oximetry:
- Just before and 3 months after T/A; or
- At baseline and after 3 months awaiting surgery (control).
- Outcomes were proportions of patients:
- With baseline McGill Oximetry Score (MOS; proxy for apnea-hypopnea index) >1 achieving 1 at follow-up; and
- With baseline ≥3.5 episodes/hour of oxygen desaturation of Hb index (ODI) achieving
- Funding: None.
- With MOS >1 at baseline:
- MOS of 1 achieved in 12/17 (70.6%) in the T/A group vs
- 10/21 (47.6%) in control group (P=.14).
- Among children with ODI ≥3.5 at baseline:
- OR, 14.0 (95% CI, 2.9-68.4; P<.001>
- Number needed to treat to prevent abnormal follow-up ODI: 3.
- Small single-center study.
- Many unsatisfactory oximetry readings.