- Physical activity shows a dose-response benefit against cardiovascular (CV) events and all-cause mortality regardless of BP status (normal, elevated, hypertensive).
Why this matters
- The right balance of exercise in terms of its CV protection for patients with hypertension has been elusive.
- These results suggest that more exercise yields greater benefit, even with hypertension.
- Compared with no activity, for patients with stage I hypertension, risk (adjusted HR; 95% CI) for all-cause mortality was:
- Light activity: 0.78 (0.72-0.84; P<.001>
- Moderate-high activity: 0.69 (0.63-0.75; P<.001>
- Prospective study that included 18,974 people, ages 20-98 years; mean follow-up, 23.4±11.7 years.
- Activity was self-reported.
- Hypertension threshold in this study was 90-99/140-159 mmHg.
- Population was all white.