- Declines in the ability to perform activities of daily living (ADL) and mental health-related QoL are significantly associated with worse survival among older patients after surgery for lung cancer.
Why this matters
- Identifying patients at risk for these declines before surgery could guide a treatment plan that includes interventions aimed at addressing these issues.
- 138 patients aged ≥65 years with a first diagnosis of lung cancer, 1998-2014.
- Follow-up at 20 months after surgery.
- Funding: None.
- Median age at diagnosis was 74 years.
- 27% of patients had a decrease in Katz ADL scores at follow-up (P<.0001>
- 57% reported a significant decline in physical health-related QoL (P<.0001>
- 45% reported a decline in mental health-related QoL at follow-up, but the change was not statistically significant (P=.07).
- The number of days of poor physical health significantly increased between baseline and follow-up (5.1±8.7 vs 10.2±13.8 days; P<.0001>
- After multivariable analysis, a decline in Katz score was significantly associated with worse OS (adjusted HR, 1.78; P=.02).
- In addition, a decline in mental health-related QoL was associated with worse disease-specific OS (adjusted HR, 2.11; P=.02).