- Almost half of older men undergoing radiotherapy for prostate cancer had no/incomplete prostate-specific antigen (PSA) testing.
- No/incomplete PSA testing was associated with high-risk disease.
Why this matters
- Consider screening healthy older men who are likely to benefit from early detection and treatment.
- 54.0% underwent PSA testing with appropriate follow-up biopsy, 26.3% underwent PSA testing without biopsy, and 19.7% received no PSA testing.
- Odds of PSA testing decreased by 20% with each additional year of age (P<.001).
- PSA testing rates did not significantly differ before vs after the 2008 US Preventive Services Task Force recommendations (P=.91).
- Men without PSA testing were more likely to be diagnosed with higher stage disease (P=.002).
- PSA-tested cohort was significantly more likely to be diagnosed with low-grade disease (Grade group [GG] 1; 42.6% vs 16.7%) and less likely to be diagnosed with high-grade disease (GG4-5; 19.0% vs 41.3%).
- 51.6% of untested men were diagnosed with high-risk disease vs 23.0% of tested men.
- Untested men had higher odds of being diagnosed with high-risk disease (OR, 3.39; P<.001).
- Retrospective review of records from 1993 to 2014.
- Funding: None specified.
- Lack of comorbidity data.
- Population derived from a tertiary referral center.