Prostate cancer: tailored telephone intervention for long-term survivors

  • Skolarus TA & al.
  • J Clin Oncol
  • 29 Mar 2019

  • curated by Deepa Koli
  • Univadis Clinical Summaries
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Takeaway

  • A personally tailored, automated telephone symptom management intervention to improve self-management in long-term survivors of prostate cancer fails to improve overall Expanded Prostate Cancer Index Composite-26 (EPIC) scores vs usual care.
  • Intervention tailored to symptom area of choice showed improvement in urinary, sexual, and bowel health scores from 5 to 12 months.

Why this matters

  • Interventions focused on long-term survivors who deal with symptoms after treatment is lacking.

Study design

  • Study of 556 prostate cancer survivors (age, 40-80 years) experiencing symptom burden were randomly assigned to personally tailored, automated telephone symptom management intervention or usual care.
  • Funding: Veterans Affairs Health Services Research and Development.

Key results

  • At 5 months, mean EPIC scores were not significantly different in the intervention group vs usual care.
  • At 12 months, confidence in symptom self-management scores improved with intervention (mean difference [MD], 0.5; P=.03).
  • At 5 months, the mean appraisal of coping score was higher in the intervention group (MD, 0.2; P=.02).
  • In subgroup analysis, significant improvement in symptom focus area domains was noted with intervention from 5 to 12 months:
    • Urinary health: incontinence (MD, 3.0; P=.02) and irritative/obstructive (MD, 5.6; P<.001>
    • Bowel health (MD, 10.1; P<.001>
    • Sexual health (MD, 7.2; P<.001>

Limitations

  • May not be generalizable.

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