Prostate stones are linked to reduced sperm motility

  • Chen T & al.
  • Am J Mens Health
  • 23 May 2019

  • International Clinical Digest
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Takeaway

  • Large, coarse prostate stones may affect sperm motility.

Why this matters

  • Researchers say this is the first case-control study to evaluate the fertility effects of prostate stones.

Study design

  • Investigators studied patients with and without prostate stones who intended to conceive children (N=1303; mean age, 33.37±6.16 years; age range, 20-59 years; 725 with stones), comparing their semen parameters and hormone profiles.
  • They assigned patients with stones into 2 groups based on transabdominal ultrasound results:
    • those with discrete and small echoes (group A, 77.66%), and
    • others with coarse and large masses of multiple echoes (group B, 22.34%).
  • Funding: Shandong Province Key Research and Development Program.

Key results

  • Total sperm motility was significantly lower in group B (41.84%±17.50%) than in group A (51.78%±20.84%; P<.001 or the stone-free control group p>
  • Progressive motility also was significantly lower in group B (31.66%±14.68%) than in group A (40.17%±17.09%; P<.001 or the control group p>

Limitations

  • The study was retrospective and single-center, with a small sample size.