- Quantitative foetal fibronectin (fFN) may improve triage of patients presenting with symptoms of preterm labour (PTL) in an outpatient setting.
Why this matters
- Preterm delivery is associated with neonatal morbidity and mortality but remains difficult to diagnose correctly.
- More than 70% presenting with contractions go on to deliver full term.
- Tests to diagnose preterm labor include fFN; however, many facilities use only qualitative rather than quantitative testing.
- Overall preterm birth rate (
- The unadjusted ORs (95% CIs) for preterm birth
- ≥10: 3.39 (1.34-8.56);
- ≥50: 7.11 (3.18-15.9); and
- ≥200: 12.5 (3.54-44.1).
- Retrospective cohort study between 2015 and 2017.
- Gravidas presenting with symptoms of PTL with intact membranes between 23 and 34 weeks of gestation and with a recorded fFN test were included (447 pregnancies).
- Funding: None.
- Retrospective design.
- Patients with multiple concerning symptoms were not included.