- The incidence of noncardia gastric cancer is significantly higher in racial/ethnic minorities, whereas the rate of cardia gastric cancer is significantly higher in non-Hispanic whites (NHW).
- Incidence of noncardia increased as neighborhood socioeconomic status (nSES) decreased, but the opposite was true for cardia cancer.
Why this matters
- The findings could help clinicians develop more effective prevention and detection strategies in high-risk patient groups.
- 77,881 patients with gastric cancer from the Surveillance, Epidemiology, and End Results database.
- Funding: NIH; others.
- Compared with NHWs, minority groups had significantly lower adjusted incident rate ratios (aIRRs) for cardia but significantly higher aIRRs for noncardia cancer.
- Cardia: Noncardia: Blacks, 0.55 (95% CI, 0.52-0.59); Hispanics, 0.63 (95% CI, 0.60-0.66); Asian/Pacific Islanders, 0.59 (95% CI, 0.56-0.62); and American Indian/Alaska natives, 0.65 (95% CI, 0.53-0.79).
- Noncardia: Blacks, 2.78 (95% CI, 2.69-2.87); Hispanics, 2.82 (95% CI, 2.74-2.91); Asian/Pacific Islanders, 3.86 (95% CI, 3.75-3.97); American Indian/Alaska natives, 1.72 (95% CI, 1.50-1.97).
- Incidence of noncardia cancer increased as nSES decreased (16.6% for highest nSES vs 23.3% for lowest), whereas the inverse was true for cardia (21.2% for highest nSES vs 15.2% in the lowest).
- Retrospective study.