Refined risk group stratification in paediatric acute lymphoblastic leukemia

  • Journal of Clinical Oncology

  • Journal of Clinical Oncology
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Purpose
Minimal residual disease (MRD) and genetic abnormalities are important risk factors for outcome in acute lymphoblastic leukemia. Current risk algorithms dichotomize MRD data and do not assimilate genetics when assigning MRD risk, which reduces predictive accuracy. The aim of our study wa...