Rotavirus vaccination has reduced hospitalisations for acute gastroenteritis-related seizures in England

  • Hungerford DJ & al.
  • J Epidemiol Community Health
  • 11 Sep 2019

  • curated by Pavankumar Kamat
  • UK Medical News
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A new study published in the Journal of Epidemiology and Community Health suggests that hospitalisations for seizures associated with acute gastroenteritis (AGE) have decreased among children aged

Researchers used aggregated records from the Hospital Episode Statistics to examine changes in monthly hospital admissions for seizures among children aged

Among children who were hospitalised, there was a decline in the incidence of any seizures and febrile seizures associated with AGE by 23% (95% CI, 11-33%) and 31% (95% CI, 19-41%), respectively, after the introduction of rotavirus vaccination. The declines in the incidence of febrile seizures were higher during the rotavirus season (49%; 95% CI, 37-58%) than during out of season (13%; 95% CI, −4 to 28%), and had no relationship with the introduction of pneumococcal conjugate vaccine. Small reductions were observed in any seizures (4%; 95% CI, 0-8%) and febrile seizures (10%; 95% CI, 2-16%) with any co-diagnosis.

The authors concluded: "Our study confirms that rotavirus vaccination brings benefits beyond the cardinal symptoms of diarrhoea and vomiting that are associated with rotavirus disease."