Simplified criteria for lung cancer prescreening

  • Triplette M & al.
  • Ann Am Thorac Soc
  • 12 Jul 2019

  • curated by Kelli Whitlock Burton
  • Univadis Clinical Summaries
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Takeaway

  • A simple list of prescreening criteria, including smoking status and current smoking intensity, could help clinicians better identify patients who are most likely to pass eligibility for lung cancer screening.

Why this matters

  • Adding info on current smoking use to electronic health records (EHRs) data could allow for prescreening to quickly determine which patients should undergo formal eligibility review.

Study design

  • 235,517,739 adults from the National Health and Nutrition Examination Survey.
  • Simplified criteria included age 55-77 years plus ever smoker, current smoker or former smoker who had quit half pack per day, current cigarette smoker of >1 pack per day.
  • Funding: Fred Hutchinson Cancer Research Center.

Key results

  • 3.8% were eligible for lung cancer screening.
  • Age and smoking status (current, former, never) correctly identified people who were eligible for lung cancer screening (area under the curve [AUC], 0.92; 95% CI, 0.91-0.92).
  • For age-eligible people, smoking status alone yielded good predictive value (AUC, 0.85; 95% CI, 0.84-0.86), but ever smoker did not.

Limitations

  • Retrospective study.