Soy consumption may lower T2DM risk

  • Diabetes Res Clin Pract

  • from Pavankumar Kamat
  • UK Medical News
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Soy consumption may reduce the risk for type 2 diabetes mellitus (T2DM), especially in women and Asians, a new meta-analysis published in the journal Diabetes Research and Clinical Practice suggests.

For this meta-analysis, researchers conducted a literature search on PubMed, Web of Science, and Embase and identified 8 observational studies (6 cohort; 2 cross-sectional) with 19 reports on soy consumption and T2DM incidence and 7 reports on soy constituents and risk for T2DM.

There was a significant inverse association between soy food consumption and risk for T2DM (relative risk [RR], 0.77; 95% Cl, 0.066-0.91). Consumption of soy protein and isoflavones significantly lowered the risk for T2DM (RR, 0.88; 95%CI, 0.80-0.97). A subgroup analysis revealed that soy consumption had a significant protective effect in women (RR, 0.65; 95% CI, 0.49-0.87) and Asian ethnicity (RR, 0.73; 95% CI, 0.61-0.88) with T2DM.

According to the authors, further studies are required to determine mechanisms underlying the effects of a high soy diet and active soy compounds and to optimise dietary soy content for health benefits in human beings. Considering the fact there were limited studies in this meta-analysis, they call for future research with well-designed cohort or interventional studies to confirm the findings of this meta-analysis.