- Abdominal pain and nausea may predict Group A streptococcal (GAS) pharyngitis in male pediatric patients, but not females.
Why this matters
- Young children suffering from GAS do not always complain of a sore throat, according to one study.
- Children <3 y may not present with other typical GAS symptoms like anterior cervical lymphadenopathy and tonsillar exudates.
- Gastrointestinal (GI) symptoms such as pain are common in children with GAS, but studies attempting to use GI symptoms to predict GAS have been inconsistent.
- Retrospective cross-sectional study of 5755 children, aged <15 y presenting with fever between June 1, 2011 and January 18, 2015.
- Funding: None.
- 331 patients were coded as having GAS pharyngitis, who were either clinically detected (n=113) or diagnosed with rapid tests (n=218).
- Among children with abdominal pain, rapid test confirmed GAS pharyngitis in 9.2% (11/120) of boys vs 2.3% (3/128) of girls (P=.026).
- Among children with nausea, 10.3% (7/68) of boys and 4.0% (2/50) of girls were confirmed with GAS pharyngitis (P=.30).
- No child under <3 y having abdominal pain or nausea was confirmed with GAS pharyngitis.
- Sensitivity of rapid test is lower than throat culture.
Coauthored with Anand Ramanathan, PharmD