Findings from a new analysis suggest stroke could more than double the risk of dementia.
Researchers analysed data from 36 studies of prevalent stroke that included 1.9 million participants and 12 studies of incident stroke that included 1.3 million participants to examine the relationship between stroke and all-cause dementia risk.
Both prevalent and incident strokes were identified as strong independent risk factors for all-cause dementia. Prevalent stroke was associated with almost 70 per cent greater risk of all-cause dementia (hazard ratio [HR] 1.69; 95% CI 1.49-1.92; P<.00001 while incident stroke was associated with more than double risk of dementia ci p the authors noted that significant heterogeneity observed and association prevalent appeared stronger in men.>
This latest study builds on previous research which had established the link between stroke and dementia, though had not quantified the degree to which stroke actually increased dementia risk.
Presenting their findings in Alzheimer's & Dementia: The Journal of the Alzheimer's Association, the authors said, given the consequences for people with dementia and their families and the significant implications for social and healthcare costs, stroke prevention strategies should be integrated into multimodal health interventions to reduce dementia risk.