- A pattern of higher consumption of sugar-sweetened beverages is linked to higher odds of chronic kidney disease (CKD).
Why this matters
- Findings contribute to a growing body of evidence pointing to negative consequences of consuming soda and other sweetened beverages.
- Analysis of data for 3003 black individuals (mean age, 54±12 years; 64% women) participating in the prospective, community-based Jackson Heart Study.
- Beverage intake assessed at baseline using a food frequency questionnaire.
- Funding: Jackson Heart Study funded by National Heart, Lung, and Blood Institute and the National Institute on Minority Health and Health Disparities.
- Mean baseline estimated glomerular filtration rate (eGFR) (in mL/minute/1.73 m2), 98.
- Over a median follow-up of 8 years, 185 participants (6%) developed incident CKD, defined as eGFR
- In multivariate analysis, principal component analysis-derived pattern consisting of a higher consumption of soda, sweetened fruit drinks, and water was tied to 61% higher odds of CKD (aOR for third vs first tertile, 1.61; 95% CI, 1.07-2.41).
- Analysis adjusted for total energy intake, age, sex, education, BMI, smoking, physical activity, hypertension, diabetes, cholesterol, cardiovascular disease history, and baseline eGFR.
- Association was stronger for consumption pattern rather than individual drinks within that pattern.
- Self-reported dietary intake.
- Potentially nongeneralizable.