Sugar-sweetened drinks tied to CKD risk

  • Rebholz CM & al.
  • Clin J Am Soc Nephrol
  • 27 Dec 2018

  • curated by Yael Waknine
  • Clinical Essentials
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • A pattern of higher consumption of sugar-sweetened beverages is linked to higher odds of chronic kidney disease (CKD).

Why this matters

  • Findings contribute to a growing body of evidence pointing to negative consequences of consuming soda and other sweetened beverages.

Study design

  • Analysis of data for 3003 black individuals (mean age, 54±12 years; 64% women) participating in the prospective, community-based Jackson Heart Study.
  • Beverage intake assessed at baseline using a food frequency questionnaire.
  • Funding: Jackson Heart Study funded by National Heart, Lung, and Blood Institute and the National Institute on Minority Health and Health Disparities.

Key results

  • Mean baseline estimated glomerular filtration rate (eGFR) (in mL/minute/1.73 m2), 98.
  • Over a median follow-up of 8 years, 185 participants (6%) developed incident CKD, defined as eGFR
  • In multivariate analysis, principal component analysis-derived pattern consisting of a higher consumption of soda, sweetened fruit drinks, and water was tied to 61% higher odds of CKD (aOR for third vs first tertile, 1.61; 95% CI, 1.07-2.41).
    • Analysis adjusted for total energy intake, age, sex, education, BMI, smoking, physical activity, hypertension, diabetes, cholesterol, cardiovascular disease history, and baseline eGFR.
  • Association was stronger for consumption pattern rather than individual drinks within that pattern.

Limitations

  • Self-reported dietary intake.
  • Potentially nongeneralizable.

Please confirm your acceptance

To gain full access to GPnotebook please confirm:

By submitting here you confirm that you have accepted Terms of Use and Privacy Policy of GPnotebook.

Submit