The effects of exercise on the lipid profile: A meta-analysis | Atherosclerosis

Access to the full content of this site is available only to registered healthcare professionals. Register to read more
  • Regular aerobic exercise led to positive changes in the lipoprotein subclass profile across ten different exercise groups from six exercise training studies that varied in the program type and participating populations.


  • A meta-analysis of 1555 adults from six studies, which included10 distinct exercise programs: APOE (N = 106), DREW (N = 385), GERS (N = 79), HERITAGE (N = 715), STRRIDE I (N = 168) and II (N = 102).
  • Nuclear magnetic resonance spectroscopy was used to quantify average particle size, total and subclass concentrations of very low-density lipoprotein, low-density lipoprotein, and high-density lipoprotein particles (VLDL-P, LDL-P, and HDL-P, respectively) before and after exercise.

Key Results
  • Regular exercise induced significant decreases in the concentration of large VLDL-P, small LDL-P, and medium HDL-P and mean VLDL-P size.
  • Re...