- Black women, Hispanic women, and those aged
Why this matters
- Database covers 99% of US population.
- TNBC is the most aggressive breast cancer subtype.
- Findings confirm results of smaller epidemiologic studies and highlight the need for more frequent screening of at-risk populations.
- Retrospective, population-based study of 1,151,724 breast cancer cases (2010-2014).
- Funding: NIH.
- TNBC accounted for 8.4% of all breast cancer cases.
- TNBC likelihood was highest among black (vs white) women (OR, 2.27; 95% CI, 2.23-2.31) and Hispanic women (OR, 1.22; 95% CI, 1.189-2.247 vs white women) in unadjusted analyses.
- TNBC odds were highest among women
- TNBC odds were highest among women with stage ≥III cancer by the American Joint Committee on Cancer (stage III: OR, 1.70; 95% CI, 1.675-1.722; stage IV: OR, 1.47; 95% CI, 1.431-1.511) in unadjusted analyses.
- Results were similar in adjusted analyses.
- Study focused more on stage ≥III tumors with highest morbidity and mortality.