Tongue cancer: study nixes link between younger age, poor prognosis

  • Oliver JR & al.
  • Head Neck
  • 15 Apr 2019

  • curated by Brian Richardson, PhD
  • Univadis Clinical Summaries
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Takeaway

  • Contrary to prior reports, younger age was not associated with poor survival of patients with oral tongue squamous cell carcinoma (OTSCC) in a review of the National Cancer Database.

Why this matters

  • Population-based study contradicts prior small cohort studies and suggests that younger patients actually have better survival.

Key results

  • Patients aged
  • After propensity score matching, patients
  • Multivariate factors for mortality included male sex (HR, 1.26; P<.001 black race comorbidities stage iii-ivb ivc unknown tumor high grade lymphovascular invasion extracapsular extension radiotherapy after surgery chemotherapy rt and positive surgical margins>

Study design

  • 22,930 patients with OTSCC, 9.9%
  • Funding: None disclosed.

Limitations

  • Retrospective study.

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