Treadmill time under 9 minutes doubles risk of death | ACC

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  • In patients referred for stress testing, decreasing exercise time was associated with increased risk of death in both genders. 

Why this matters

  • Physical inactivity is a major health problem. 

Key results

  • A total of 126,356 patients (mean age 53.5 years, 59% were male) were included; at 10-year follow-up, 9929 (8%) had died.
  • Median exercise time was 570 seconds in males and 480 seconds in females.
  • Using the median exercise time of 540 seconds, lower exercise time was associated with a higher risk of death (hazard ratio [HR] 1.22; P <0.001].
  • After adjusting for cardiac risk factors, an exercise time <540 seconds conferred about a two-fold increased risk of death (HR 2.06; P <0.001] and was the major determinant of death after age. 

Study design ...