Due to the rapidly changing nature of the COVID-19 pandemic, we at Univadis would like to share with you the most impactful and clinically relevant articles across our network from the past week.
Some of these articles are only published in local languages, but we have tried to summarize the key points for you below and link to the original source of each article in case you would like to read more, with languages other than English noted in brackets.
This is a snapshot of emerging best-practices during a rapidly evolving pandemic. Any and all information currently available related to COVID-19 is subject to change as more details become available. Some of the information below may also be contradicted by local or global health authorities. You can find all of the most up-to-date COVID-19 coverage on your local Univadis site or smartphone application.
We hope this information will be useful to your ongoing medical care for all patients, whether directly involved with COVID-19 or not.
- Several US cardiology associations warned of serious arrhythmia risk with several exploratory COVID 19 treatments. They emphasized that monitoring is crucial and to avoid hydroxychloroquine and azithromycin in patients with existing QT issues. Their statement also includes a helpful tabulation of relevant medications and their associations with adverse cardiac events.
- Proposal for international standards for lung ultrasound in COVID-19 patients: The authors suggest a detailed, quantitative, and reproducible protocol to facilitate screening and detection. They also link to an international database for uploading results.
- The UK’s COVID Trauma Response Working Group has issued advice for healthcare professionals to manage stress. This includes taking breaks during and time out between shifts, reaching out for help if support is needed, and more.
- Teleconsultations with physicians [French] in France have risen from less than 10,000 per week to 80,000 the week of 16 March to 486,369 the week of 23 March! These involve at least one-third of practicing physicians and the national health insurance organization, Assurance Maladie, acknowledged their relevance both for patients with non-severe COVID-19 cases or other health problems.
- A Max Planck Institute study [German] reports that measures to prevent COVID-19 spread in Germany are starting to show results. The model used allows for an estimation of the effects of limitations implemented distinct times in March. While encouraging, experts still advise that limitations are still necessary.
- A national Italian epidemiological preprint reports that of the first 62,843 cases of COVID-19, 71.6% occurred in Lombardy, Veneto, and Emilia-Romagna, R0 was 2.5-3, and doubling time was 2.7-3.2 days. Advanced age, male sex, and presence of comorbidities were all associated with worse outcomes.
- The international SOLIDARITY trial testing multiple treatments for COVID-19 will also be conducted in Italy, involving 32 clinical centers [Italian].
- The Spanish Health Minister stated that the COVID-19 epidemic peak incidence had been reached, but the restrictions would remain in place until careful analysis on how to proceed had been conducted. In the announcement, the Health Minister noted a 2% daily increase in detected cases, 6% increase in number recovered, and 3% increase in deaths.