- Medical expulsive therapy (MET) does not increase the likelihood of spontaneous stone passage (SSP) in patients with acute ureteric colic.
- White blood cell count (WBC), neutrophil count, and C-reactive protein (CRP) levels do not help predict SSP.
Why this matters
- Clinicians should rely on stone size and position to determine the need for active stone treatment.
- Researchers studied patients with acute ureteric colic and single ureteric stones who were discharged with conservative management (N=2518; median age, 47 years; median stone size, 4 mm).
- They used multivariable mixed effects logistic regression to examine associations with SSP.
- Funding: British Association of Urological Surgeons; British Journal of Urology International; Urology Foundation; Ferring Pharmaceuticals; Rosetree’s Trust; Action Bladder Cancer UK.
- Overall SSP rate: 74% (1874/2518).
- None of the following predicted SSP (aOR; 95% CI):
- MET: 1.11 (0.76-1.61; P<.6>
- WBC: 0.97 (0.91-1.04; P=.39).
- Neutrophils: 1.06 (0.99-1.13; P=.11).
- CRP: 1.00 (0.99-1.00; P=.17).
- SSP was more likely for smaller stones and those farther down the ureter.
- The study was observational and retrospective.