- Ultrasound (US)-guided radiofrequency ablation (RFA) is associated with >90% therapeutic success rate in patients with benign thyroid nodules, with comparable results in patients with predominantly solid (PS) vs predominantly cystic (PC) lesions.
Why this matters
- Few studies have addressed whether solid vs cystic lesion status affects the outcomes of US-guided RFA.
- After the first ablation, rates of therapeutic success (volume reduction >50% at 6 months) were 78.9% in patients with PC lesions and 78.2% in patients with PS lesions (P=.439).
- After the final ablation, rates of therapeutic success were 91.4% in patients with PC lesions and 93.4% in patients with PS lesions (P=.148).
- The most common complications were localized edema (1.9% in PC group; 1.3% in PS group), transient voice change (0.5% in PC group; 0.3% in PS group), and infection (0.3% in PC group; 0.3% in PS group).
- Small thyroid nodule volume (
- 1000 patients with 1619 thyroid nodules were treated with US-guided RFA and analyzed for outcomes.
- Funding: Korea University.
- Retrospective analysis.