- Diagnosis of uterine fibroids prior to or during pregnancy increases risk for preterm birth and cesarean delivery (CD).
Why this matters
- 10% of pregnant women have uterine fibroids.
- Retrospective historical cohort study.
- Cohort obtained from the Danish National Patient Registry and the Danish National Birth Registry (n=92,696 pregnancies).
- Women with fibroids identified through diagnosis and operation codes.
- Cohort divided into 4 groups:
- Group 1: no fibroid codes (n=91,292);
- Group 2: fibroid diagnosis code before, during, or up to 1 year after delivery and with no operation codes before pregnancy (n=124);
- Group 3: fibroid diagnosis code given >1 year after delivery (n=963); and
- Group 4: fibroid operation code before pregnancy (n=317).
- Funding: No funding for study; 1 author cited Danish university and government funding.
- Risk for preterm birth increased in group 2: OR, 2.3 (95% CI, 1.30-3.96).
- Risk for CD increased in group 2: OR, 2.2 (95% CI, 1.50-3.21).
- The risk for postpartum hemorrhage (PPH), placental abruption, and fetal growth restriction was not increased in women with a fibroid diagnosis code.
- Retrospective data.
- Coding errors possible.