- Neurogenic bladder (NB) is common among babies born with congenital Zika syndrome (CZS) and microcephaly.
Why this matters
- Without timely intervention, NB can cause irreversible renal damage; lack of awareness about the association between CZS and NB delays investigation and treatment.
- Researchers studied babies born with neurological impairment caused by CZS (n=69; mean age, 13.6 months; age range, 2-23 months; 36 girls), evaluating them for NB following International Children’s Continence Society guidelines.
- Funding: Federal Government of Brazil.
- Urodynamic studies for all patients had abnormal results consistent with NB.
- Most patients (91.3%) had overactive bladder with increased pressures and reduced capacity for age.
- Only 26 patients (38%) were able to void to completion at the end of the urodynamic studies; 43 (62%) had elevated postvoid residual holding averaging 36% of their measured bladder capacity.
- The cause of NB secondary to CZS remains unclear.
- The role of Zika virus infection in the urological system is unknown.