Recommended on Univadis

Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma
  • The New England Journal of Medicine
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Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma

Patients with BRAF mutations who received adjuvant therapy with dabrafenib and trametinib had a 53% lower risk of 3-year recurrence than those who received placebo.

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  • The New England Journal of Medicine
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Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma

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  • The New England Journal of Medicine
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Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

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  • The New England Journal of Medicine
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Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer

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  • UK Medical News
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ED admission avoidance strategies are working

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  • Clinical Summaries from Pain Pract
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Low back pain: electrothermal therapy proves cost-effective

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  • Clinical Summaries from Br J Psychiatry
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Are antidepressants effective for depression in schizophrenia?

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  • EAS Snapshots
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The smoking gun in atherosclerosis– LDL or immune cells? – Plenary lecture at EAS 2017 in Prague

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  • Global Medical News
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Early exposure to pet and pest allergens may prevent asthma in children

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Professional & Business

  • International Medical Press

NICE approves nivolumab for lung cancer

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  • International Medical Press

Improve access to end of life care, says report

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  • International Medical Press

Prioritize respiratory care services, urges BLF

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  • International Medical Press

NHS workers campaign for 3.9% pay rise

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  • International Medical Press

Health secretary announces new plans to tackle sepsis

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  • International Medical Press

Antibiotics against Group B Strep advised for women in early labour

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New on Univadis

Older people with diabetes at higher risk for fracture
  • Global Medical News
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Older people with diabetes at higher risk for fracture

A new study suggests deficits in cortical bone density and microarchitecture may be responsible.

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Beta-blockers unnecessary after myocardial infarction
  • Global Medical News
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Beta-blockers unnecessary after myocardial infarction

The benefits of beta-blockers among patients taking statins and ACE inhibitors/ARBs may be limited.

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  • Clinical Summaries from Stroke
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Can fibrin clot permeability predict stroke, bleeding in anticoagulated patients with Afib?

Fibrin clot permeability is commonly used to determine fibrin clot structure.

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Lung cancer patients in England get much needed access to nivolumab
  • UK Medical News
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Lung cancer patients in England get much needed access to nivolumab

Drug to be made available through the Cancer Drugs Fund.

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  • Clinical Essentials from BJU Int
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Penile SCC: front-line dacomitinib shows promise in phase 2 trial

Dacomitinib is an irreversible, pan-epidermal growth factor receptor inhibitor.

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  • Clinical Essentials from J Clin Oncol
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Which NHL survivors have greatest risk for HF?

The study recommends preventive strategies in the newly diagnosed.

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Huntington’s disease: study uses progression measures to identify the disease modifiers
  • The Lancet Neurology
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Huntington’s disease: study uses progression measures to identify the disease modifiers

Findings from genome-wide association study using TRACK-HD data

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  • Global Clinical Summaries from Pharma Res Per
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Montelukast: evidence for neuropsychiatric adverse effects

Postmarketing surveillance reveals disproportionate rates of depression, aggression, and suicidality.

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  • Global Clinical Summaries from Am. J. Nephrol
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Dialysis: low testosterone tied to higher mortality risk in men

Data from a large US population study.

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  • Global Clinical Summaries from Vaccine
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Pediatric pneumonia hospitalization with 10- and 13-valent pneumococcal vaccines

Novel vaccines offer reduced hospitalization risk compared with older or no vaccine.

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  • Global Clinical Summaries from Lancet Psychiatry
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In mania, olanzapine is less effective in mild illness

Clinicians should consider benefit-to-risk ratio with olanzapine for patients with mild mania symptoms.

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  • Global Clinical Summaries from J Clin Rheumatol
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Psoriatic arthritis: interleukin inhibitors show promise

Results from a meta-analysis.

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  • Global Clinical Summaries
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FDA: safe to prescribe benzodiazepines to patients treated for opioid addiction.

There are still many risks for their concomitant use.

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Women with AF and diabetes have higher mortality and more CV events | EASD
  • Conference reports - RSi Communications
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Women with AF and diabetes have higher mortality and more CV events | EASD

Mortality occurred in 45.8% of men vs 53% of women.

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