Recommended on Univadis

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Asthma: Children more vulnerable to traffic pollutants | Meta-analysis

Largest and most up-to-date review and analysis of current evidence.

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Paracetamol-induced liver failure: monocytopenia possible early predictor for mortality?

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High risk for VTE with testosterone use

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Prolonged sedentary bouts detrimental for children | UK study

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Incretins not linked to acute/chronic pancreatitis in current users | UK study

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Botox injection: who is at risk for urinary retention?

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Abdominal aortic aneurysm: fewer repair, more deaths in the UK than the United States | NEJM

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Most add-on fertility treatments lack evidence | UK study

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Antidepressant prescriptions in the UK doubled over the last 2 decades

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Professional & Business

  • International Medical Press

Workload affecting junior doctors’ training, says GMC

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  • International Medical Press

Doctors should be in charge of hospitals, says Jeremy Hunt

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  • International Medical Press

Agency doctor spend putting departments at risk of closure

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  • International Medical Press

Give pharmacists more prescribing rights, says RPS

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  • International Medical Press

Ambulances too slow to reach patients, investigation finds

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  • International Medical Press

On-the-job training for nurses

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New on Univadis

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Stroke: right insular involvement linked to poor outcomes

The associations between insular involvement and stroke outcomes are controversial.

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  • Clinical Essentials from FDA
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FDA approves empagliflozin for CV mortality reduction in type 2 diabetes

Drug was first to show survival benefit beyond glucose-lowering.

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  • Clinical Essentials from J Hepatol
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HCV-1b: DCV/ASV highly effective, beneficial after age 80

Clearance rates top 95%, with survival benefit.

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  • Clinical Essentials from Congenit Heart Dis
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Strep infective endocarditis has increased considerably as a cause of pediatric IE

Although the microbiology has shifted, rates have remained stable during the last decade.

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  • Clinical Essentials from Diabetes Care
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Which hormonal contraceptives are safest for women with diabetes?

Most prior studies investigating progestin-only contraceptives and thromboembolism have not included women with diabetes.

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  • Clinical Essentials from JAMA Oncol
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Clear-cell RCC: rotating first-line strategy fails to show benefit

Single-agent VEGF-inhibitor remains the first-line treatment of choice for metastatic clear cell renal cell cancer.

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  • Clinical Essentials from Int J Colorectal Dis
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Rectal adenocarcinoma: pCR improves survival, can it be predicted?

Height above anal verge retained prognostic significance in multivariate analysis.

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  • Clinical Essentials from J Cachexia Sarcopenia Muscle
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DLBCL: can skeletal muscle density predict outcomes?

New marker may avoid prognostic limitations of sarcopenia.

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  • Clinical Essentials from Gynecol Endocrinol
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HRT: combining estradiol with progesterone raises risk for breast cancer

Meta-analysis shows no increased risk with estradiol alone.

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  • Clinical Essentials from Onco Targets Ther
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Talimogene laherparepvec tops GM-CSF in advanced melanoma

Talimogene laherparepvec yielded better responses in patients with stage IIIB, IIIC, and IVM1a melanoma.

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Vaccine: Monthly Essentials November 2016
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Vaccine: Monthly Essentials November 2016

HPV vaccine and inconsistent condom use | Tdap vaccination during pregnancy and microcephaly risk | Herd effect from influenza vaccination?

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  • Clinical Essentials from BJOG
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Care after stillbirth focused on medical testing and not psychosocial support

Geographical differences seen; practice guidelines needed.

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  • Clinical Essentials from Aliment Pharmacol Ther
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HCV-4: dual-DAA regimen shows 100% efficacy

Results of the phase 3 PLUTO study.

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  • Clinical Essentials from Stroke
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Stroke: right insular involvement linked to poor outcomes

The associations between insular involvement and stroke outcomes are controversial.

Read more