224hrs 48mins - Expert presentations By Professor David Livermore
Future developments in antimicrobial agents
Professor David Livermore highlights increasing resistance and the major bacterial challenges we face. Beta-lactams, the most widely used antibiotic are losing their efficacy. However, there is hope for antimicorbial agents. Cefiderocol, murepavadin and gepotidacin/zoliflodacin all show promise in replacing spent antibiotics. Further, non-antibiotic approaches and improved molecular diagnostics, while not currently comprehensive, could revolutionise the field.
198hrs 36mins - Expert presentations By Professor Laura Bowater
Antimicrobial resistance: antibiotic stewardship in the UK
Professor Laura Bowater sets the scene with the global threat of antimicrobial resistance (AMR). She discusses the causes of AMR, and how antibiotic stewardship can prevent it's spread. Responsible usership, auditing and a strong clinical leadership are all key components of antibiotic stewardship.
215hrs 16mins - Expert presentations
Antimicrobial resistance: epidemiology and experience in the UK
Dr Matt O'Shea and Dr Ed Bevan discuss the basic mechanisms of antimicrobial resistance and the predicted clinical cost in the UK. They elaborate on the epidemology of a number of known and prevelant resistant bacterium in the UK and explain how antimicrobial stewardship, screening and surveillance are helping to prevent the spread of such bacteria. Finally, they discuss a real patient case.
237hrs 30mins - Expert presentations By Thierry Naas
Epidemiology of multidrug resistant Gram-negative bacteria: Are we close to the « post antibiotic era »?
Multidrug resistant bacteria are developing so fast that the burden of deaths due to these bacteria could be 10 million lives/year by 2050 - with an estimated cost of 1,000 trillion USD! In this short presentation, Dr. Naas highlights this crucial problem by explaining the mechanisms behind Gram-negative bacteria resistance as well as the epidemiology of extended spectrum ß-lactamase and carbapenem-resistance. He also presents possible solutions that can be used in this time-sensitive fight.