Recommended on Univadis

Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma
  • The New England Journal of Medicine
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Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma

Patients with BRAF mutations who received adjuvant therapy with dabrafenib and trametinib had a 53% lower risk of 3-year recurrence than those who received placebo.

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  • The New England Journal of Medicine
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Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV Melanoma

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  • The New England Journal of Medicine
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Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

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  • The New England Journal of Medicine
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Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer

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  • Clinical Summaries from J Stroke Cerebrovasc Dis
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Urinary incontinence and IUCs predict death in stroke patients

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  • Clinical Summaries from PLoS Med
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Does BP self-monitoring help in hypertension?

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  • JAMA Oncology
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Overall survival in GE adenocarcinoma: postoperative observation vs adjuvant chemotherapy

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  • The Lancet
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Higher burden of chronic health conditions among childhood cancer survivors

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  • Global Medical News
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Montelukast linked with neuropsychiatric side effects

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Professional & Business

  • International Medical Press

90% of GP surgeries rated good or outstanding by CQC

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  • International Medical Press

NICE approves nivolumab for lung cancer

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  • International Medical Press

Improve access to end of life care, says report

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  • International Medical Press

Prioritize respiratory care services, urges BLF

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  • International Medical Press

NHS workers campaign for 3.9% pay rise

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  • International Medical Press

Health secretary announces new plans to tackle sepsis

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New on Univadis

Lung and stomach cancer are the top cancer killers in England
  • UK Medical News
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Lung and stomach cancer are the top cancer killers in England

Even though survival has increased in recent years, the effect of cancer on life expectancy varies across socio-economic groups.

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Quality standard for end of life care in paediatric patients
  • UK Medical News
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Quality standard for end of life care in paediatric patients

Guidance also includes support for family members and carers.

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  • Clinical Summaries from Br J Cancer
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Does smoking cessation after diagnosis improve survival in patients with cancer?

The benefits of smoking cessation varied across different cancers.

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  • Clinical Essentials from J Natl Cancer Inst
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Breast cancer: extended AI therapy tied to CV events, bone fractures

Meta-analysis suggests need for greater surveillance if AI therapy is extended past 5 y.

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  • Global Clinical Summaries from Lancet Respir Med
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Earlier successful extubation if sedation halted right after surgery

Results from the Strategy of Optimized Sedation­-Ventilation (SOS­Ventilation) study.

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  • Global Clinical Summaries from Int Clin Psychopharmacol
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In severe resistant depression, SGA supplementation helps

Augmentation recommended as first-line treatment in severe treatment-resistant depression with specific comorbidities.

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  • Global Clinical Summaries from Toxicol Appl Pharmacol
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Synthetic DMARDS may explain the link between RA and dementia

RA is known to be associated with dementia.

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  • Clinical Essentials from J Clin Oncol
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Prostate cancer: comorbidity does not raise cancer-specific mortality

Data from a large observational study.

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Pain and Opioid Abuse: Monthly Essentials September 2017
  • Global Monthly Essentials
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Pain and Opioid Abuse: Monthly Essentials September 2017

TMS in migraine | Ibuprofen lozenge for sore throats | Reducing nipple pain in breastfeeding.

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  • Clinical Essentials from J Natl Cancer Inst
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Early breast cancer: no survival benefit for 5 vs 2.5 y of extended endocrine therapy

The IDEAL trial did find the reduction of second primary breast cancer with 5 y extra treatment.

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Ghrelin linked to cognitive impairment in elderly with T2D | EASD
  • Conference reports - RSi Communications
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Ghrelin linked to cognitive impairment in elderly with T2D | EASD

Serum ghrelin was significantly lower in patients with MCI

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Simple clinical test can reveal underlying obstructive sleep apnea | EASD
  • Conference reports - RSi Communications
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Simple clinical test can reveal underlying obstructive sleep apnea | EASD

Analysis of cardiorespiratory reflex imbalance can show the post-effects of transient relief of subclinical hypoxia.

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  • Global Clinical Summaries from Am J Prev Med
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Young adult women less likely to receive diabetes prevention efforts

Waiting until pregnancy to deliver lifestyle interventions may be “too little, too late.”

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  • Global Clinical Summaries from Epilepsia
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Epilepsy: watch out for bone mineral loss in children

Antiepileptic drugs may take their toll on bones.

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