Findings support utility of ambulatory blood pressure monitoring early in pregnancy.
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Nocturnal hypertension in high-risk mid-pregnancy predicts subsequent pre-eclampsia/eclampsia -
A meta-analysis of 41 randomised trials.
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Grey matter development in adolescents may be altered by the gene mutation.
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Aspirin use may not provide mortality benefit among adults without established cardiovascular disease Modest reduction in myocardial infarction risk comes at a cost of increased major bleeding.
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Adiposity tied to risk for renal function decline A meta-analysis from the Chronic Kidney Disease Prognosis Consortium.
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HCV: post-DAA HCC risk higher with advanced fibrosis SVR reduces, but does not eliminate, HCC risk.
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How does dapagliflozin perform in the real world? Reductions in HbA1c, systolic BP, body weight, BMI were at least as steep as in clinical trials.
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Physical activity tied to better cognition despite brain pathologies Physical activity, motor skills may attenuate effects of dementia.
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1 in 4 US antibiotic prescriptions found unnecessary A study of 19.2 million privately insured children and nonelderly adults in 2016.
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STROMBOLI: targeted therapies safe, effective for mCRC in elders Observational study suggests similar response vs younger counterparts.
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CKD: meta-analysis supports change in albuminuria as a surrogate for progression Association is stronger in patients with high baseline ACR.
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Hypertensive disorders of pregnancy tied to anxiety in teen offspring Anxiety disorders were more than twice as likely in children of mothers with HDP.
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Elderly patients with OAB benefit from mirabegron-solifenacin combination therapy Study is first to assess long-term tolerability and effectiveness in both young and old patients.
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Chronic urticaria tied to higher risk for osteoporosis Study of >11,000 patients suggests screening is warranted.