ONCOLOGY

Consider PTR in these patients, but factor age and primary tumor site, size, and differentiation into the decision.

Severe obstructive sleep apnoea may indicate the need for endoscopic screening for Barrett's oesophagus.

Study highlights “surprisingly low” risk of lymph node metastases and micrometastases with endoscopic treatment.

The study uses a larger and more detailed database than previous work.

About half of esophageal cancers recur within 2 years after surgery with curative intent.

First phase 2 randomized trial of add-on lapatinib with perioperative chemotherapy.

No survival benefit, higher rate of recurrent laryngeal nerve palsy.

A change in the standard of care.

Data from the European Prospective Investigation into Cancer and Nutrition cohort.

Results from a large multi-institutional analysis highlight the major role of radiation dose in the choice of the optimal treatment for oesophageal cancer

In male veterans, HIV infection is associated with a higher risk for oesophageal squamous cell carcinoma, especially when CD4 count is low, but not with oesophageal adenocarcinoma or gastric cancer after adjusting for confounders.

CCRT may be a "reasonable" option, with salvage surgery for residual disease.

Posttreatment biopsies were malignancy-free in all patients.

No survival advantage with fluorouracil in dCRT for locally advanced disease.