- Among adults with impaired glucose tolerance (IGT) or newly diagnosed, drug-naive type 2 diabetes (T2D), higher total physical activity counts (TACs) are linked to greater insulin sensitivity.
- The activity is not, however, tied to better beta-cell response.
Why this matters
- Assessing the benefits of physical activity for IGT or as a lifestyle change for those newly diagnosed with T2D has been stymied by different methods, including self-report.
- This study relied on TAC measured with wrist accelerometers.
- TAC showed no association with any glucose measures, including fasting plasma or oral glucose tolerance test results.
- It was linked to higher insulin sensitivity (P=.0210).
- However, more TACs were not tied to changes in beta-cell response.
- The least active group not unexpectedly had the highest weight, waist circumference.
- Cross-sectional study, adults with IGT or drug-naive new T2D diagnosis.
- n=230, mean age 54.5 years, mean BMI 35.
- TAC was measured for 7 consecutive days and participants grouped into quartiles from high to low activity.
- Funding: NIH, ADA, some industry support.
- Usual limitations of cross-sectional designs, including allowing no inferences about causation.
- Authors say that a larger sample size might have teased out links between TAC and beta-cell response.