- Women have greater risk than men for heart failure (HF) hospitalization after acute myocardial infarction (MI).
- The risk increase sets in soon after the MI.
Why this matters
- Authors: given the early increase in risk, follow-up after discharge in the early post-MI phase may need to be evaluated to ensure optimization of outcomes.
- Cohort included 237,549 patients who had an acute MI (71.9% non-ST-elevation).
- Mean age, 66.9 years; 37.9% were female.
- Some differences in comorbidities, age, risk factor history, and revascularization rates between women and men.
- HF was more common among women at the index event:
- 34.3% vs 26.1% among men (P<.001>
- 5.4% of overall population had HF hospitalization within 6 months.
- 6.8% of women vs 4.6% of men (P<.001>
- 4.6% of the hospitalized group died during the hospitalization.
- Fatality rate was similar between women and men.
- Propensity-matched analysis showed higher HF hospitalization risk for women vs men:
- HR, 1.13 (95% CI, 1.05-1.21).
- Retrospective cohort analysis, US Nationwide Readmissions Database data from January to June 2014.
- Funding: None disclosed.
- Claims-based data.
- Outpatient HF diagnoses possibly missed.