- Heavy use of cosmetics during pregnancy is associated with an increased risk for small for gestational age (SGA) in neonates.
Why this matters
- 60%-80% of pregnant women use cosmetics, including facial creams and cleansers, mascara, foundation, eye shadow, and eyeliner.
- Cosmetics often have chemicals that are not required to be listed in the ingredients, including parabens, phthalates, and benzophenone.
- Registry-based studies show an association between cosmetics and low birth weight and infertility.
- There was no difference between risks for preterm labor, low birth weight, or macrosomia between cosmetic users and nonusers.
- Cosmetic users had a 23% increased risk for SGA: aOR, 1.23 (95% CI, 1.04-1.44).
- A positive dose response was found for cosmetic use and SGA.
- Prospective cohort study.
- Pregnant women were recruited from several hospitals and prenatal centers in China between 2016 and 2017.
- Cohort was divided into cosmetic users (n=5058) and nonusers (n=4652).
- Funding: National Center for Women and Children’s Health, China CDC.
- Subject to recall bias.
- Pathophysiology and specific chemicals associated with findings are unknown.
- Specific to the Chinese context.