Findings form a new study suggest blood type O is significantly associated with high mortality in severe trauma patients.
The study included 901 patients with severe trauma who were transported to one of two tertiary emergency critical care centres in Japan during 2013 to 2016. Patients were divided based on ABO blood type. The authors evaluated the association between the different blood types and the outcomes of all-cause mortality, cause-specific mortalities, ventilator-free days (VFD), and total transfusion volume using univariate and multivariate competing-risk regression models.
They found patients with blood type O had a mortality rate of 28 per cent compared to a rate of 11 per cent in patients with other blood types. Blood type O was significantly associated with higher cause-specific mortalities and shorter VFD compared with other blood types. However, a significant difference was not observed in the transfusion volume between the two groups.
Presenting the findings in Critical Care, the authors said further studies elucidating the mechanism underlying this association are warranted to develop the appropriate intervention. They said, however, that it would be “of great significance for clinicians to recognise the potential risk of blood type O”.