- A new model can help predict whether potential kidney donors are at risk for postnephrectomy chronic kidney disease (CKD).
Why this matters
- "Surgeons and patients could use this model to evaluate the risk of developing CKD," say researchers.
- Researchers also say that "patients who are likely to develop CKD should receive instruction about risk modification."
- Investigators studied patients who underwent donor nephrectomy with 1-year follow-up (n=440; mean age, 41.6 years; mean BMI, 23.3 kg/m2; 29.8% were smokers and 51.6% consumed alcohol).
- The researchers used a logistic regression model based on patient age and preoperative concentrations of calcium and creatinine to predict risk for CKD.
- Funding: None disclosed.
- 32.7% of patients developed first-time CKD (defined as a glomerular filtration rate of 2) by 1 year after surgery.
- The researchers’ model predicted CKD with an area under the curve of 0.796, an accuracy of 70.9%, a sensitivity of 66.2%, and a specificity of 80.6%.
- The study was single-center.
- The prediction model did not account for family history of renal disease.