- Shedding of potentially infectious 2019 novel coronavirus (COVID-2019) may occur in individuals without fever and with few or no signs of infection.
Why this matters
- It is unclear if COVID-19 viral shedding in asymptomatic persons implies transmission risk.
- Testing may be warranted in all persons with possible COVID-19 exposure, regardless of symptoms.
- 126 German nationals staying in Hubei Province were evacuated from the area on February 1 and transferred to Germersheim, Germany, to be quarantined for 14 days.
- 10 passengers were isolated during the flight: 2 had had contact with 1 person who had a confirmed COVID-19 infection, 6 showed symptoms, and 2 had been exposed to isolated family members; all 10 tested negative upon arrival.
- 116 passengers (ages 5 months to 68 years; 23 children) were screened upon landing; 1 had fever and cough but tested negative for COVID-19.
- 114 of the remaining 115 who passed triage consented to a throat swab.
- 1.8% (2/114) of this group were positive for the COVID-19-causative virus on RT-PCR (cycle threshold values for each were 24.39 and 30.25, respectively).
- Testing in culture with colon tumor epithelial cells indicated potential infectivity.
- Both patients were transferred to an infectious disease unit for evaluation/observation.
- 1 patient had faint rash, minimal pharyngitis.
- The other is reported to have remained symptom-free.
- At 7 days postadmission, both were well and afebrile.