- A meta-analysis reveals that enhanced recovery after surgery (ERAS) led to fewer complications and shorter hospital stays in patients undergoing laparoscopy for colorectal cancer.
- There was no significant difference in 30-day readmission rates or mortality.
- The multimodal program uses 17 items in an effort to reduce surgery stress, accelerate functional recovery, and reduce postoperative morbidity.
Why this matters
- Existing trials of ERAS in colorectal cancer have yielded mixed results, and previous meta-analyses relied on fewer and lower-quality trials.
- Meta-analysis of 13 studies (n=1298) conducted in China, Korea, the Netherlands, Italy, and Egypt.
- Funding: None disclosed.
- Compared with traditional care (TC), ERAS was associated with a shorter postoperative hospital stay (weighted mean difference [WMD], −2.00 days; P=.00; 12 studies).
- ERAS was associated with a shorter time to first flatus (WMD, −12.18 hours; P=.00; 9 studies) and time to first defecation (WMD, −32.93 hours; P=.00; 7 studies).
- 17.84% of ERAS patients experienced postoperative complications compared with 27.01% of TC (risk ratio, 0.59; P<.01 studies>
- There was no significant difference in 30-day readmission rates or mortality rates (5 studies).
- Significant heterogeneity in some analyses.