Cutaneous comorbidities prevalent in atopic dermatitis

  • Zander N & al.
  • J Eur Acad Dermatol Venereol
  • 13 Jul 2019

  • International Clinical Digest
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Takeaway

  • Atopic dermatitis (AD) is associated with increased risk for other skin diseases such as hand eczema and contact dermatitis, according to a cross-sectional study from Germany.

Why this matters

  • This study suggests that patients with AD should be screened for other cutaneous conditions.

Key results

  • Patients with current AD had higher prevalence of hand eczema (prevalence ratio [PR], 4.62), contact dermatitis (PR, 3.38), exsiccation dermatosis (PR, 2.19), folliculitis (PR, 1.95), and port wine stains (PR, 1.49) compared with patients without current AD.
  • AD was associated with increased odds of hand eczema (OR, 3.96; P≤.001), contact dermatitis (OR, 2.97; P≤.002), folliculitis (OR, 2.03; P≤.001), tinea corporis (OR, 2.00; P=.011), allergic asthma (OR, 2.03; P≤.001), exsiccation dermatosis (OR, 1.78; P≤.001), allergic rhinoconjunctivitis (OR, 1.56; P≤.001), and port wine stains (OR, 1.45; P=.008) in regression analysis, whereas AD was negatively associated with psoriasis (OR, 0.61; P=.024).

Study design

  • 118,939 subjects, 1.45% with AD at clinical examination and 4.95% with self-reported AD during their lifetime, were included.
  • Funding: None.

Limitations

  • Observational study design.
  • No laboratory confirmation of diagnoses.

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