- Preoperative breast MRI (pMRI) is associated with fewer total surgeries (breast-conserving surgeries [BCS], reexcision, or mastectomy) in a cohort of women newly diagnosed with pure ductal carcinoma in situ (DCIS).
Why this matters
- pMRI, which is designed to evaluate the extent of DCIS, has been controversial because of limited data on its effect on surgical management.
- Retrospective cohort (n=373) of all women with core-needle biopsy (CNB)-diagnosed DCIS 2004-2013 at a single center.
- Funding: NIH.
- No clinical differences were found between pMRI and no-pMRI groups.
- The pMRI group (vs no-pMRI group) had:
- Higher rate of additional CNB (30% vs 7%; P=.002).
- Fewer mean total surgeries (1.2 vs 1.5; P<.001>
- In the subgroup (n=245) for whom BCS was the initial surgery (rather than mastectomy), the pMRI subgroup (vs no-pMRI) had:
- Fewer mean total surgeries (1.3 vs 1.7; P<.001>
- Higher rate of single successful BCS rather than a second BCS or a mastectomy (77% vs 43%; P<.001>
- Fewer total mean surgeries (difference, −0.22 vs −0.17; P<.001>
- Higher rate of single successful BCS (20% vs 14%; P<.001>
- Single-center study.
- Nonrandomized, retrospective design.