- Among patients with depression, response and remission rates are higher among patients treated with minimally guided internet-based interventions compared with control patients, according to this meta-analysis.
- Minimal guidance was defined as being provided infrequently through electronic means, such as emails, phone calls, and e-chats after an online session.
- Outcomes were better among native-born participants than among ethnic minorities.
Why this matters
- Internet-based treatments could overcome barriers to accessibility.
- Meta-analysis of 24 randomized control trials included a total of 4889 patients with depression (internet-based intervention group, n=2514; control group, n=2375).
- Funding: None disclosed.
- Significantly higher response (OR, 2.49; P<.001 and remission p rates in the intervention vs control group.>
- Response was better among older vs younger adults (OR, 1.01; P=.03) and among native-born vs ethnic minority participants (OR, 1.66; P=.02).
- Age (OR, 1.01; P=.02), ethnicity (OR, 1.73; P=.03), and baseline depression severity (OR, 1.19; P=.04) also moderated the effects of remission.
- Limited generalizability of findings.
Coauthored with Chitra Ravi, MPharm