Depression, PTSD common after orthopedic injuries

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  • Almost one-third of victims had depression and about one-quarter had posttraumatic stress disorder (PTSD).

Why this matters

  • Treatment strategies for patients with orthopedic injury should incorporate the potential for depression and PTSD.

Study design

  • The researchers conducted a meta-analysis of 27 studies (n=7109).
  • Funding: Source of funding not disclosed.

Key results

  • 32.6% of individuals who had experienced an orthopedic injury had depression (22 studies; n=6005), and 26.6% had PTSD (11 studies; n=1867).
  • 16.8% had both depression and PTSD (3 studies; n=443).


  • The study cannot prove causation.
  • Most studies had a short follow-up.
  • Definitions of depression and PTSD varied widely between studies.