Postmenopausal women with a higher intake of artificially sweetened beverages (ASBs) may have a higher risk of stroke, coronary heart disease (CHD), and all-cause mortality, according to new research published in Stroke.
The study included 81,714 women from the Women’s Health Initiative Observational Study, a longitudinal study of the health of 93,676 postmenopausal women of ages 50 to 79 years at baseline. Most of the participants were infrequent consumers of ASBs (≤1 ASB per week), while 5.1 per cent consumed two or more ASBs daily.
In multivariate analyses, those consuming the highest level of ASB compared to infrequent consumers had an approximately 23 per cent greater likelihood of stroke, 31 per cent greater likelihood of ischaemic stroke, 29 per cent greater likelihood of CHD and 16 per cent greater risk of all-cause mortality.
In women with no prior history of cardiovascular disease or diabetes mellitus, high consumption of ASBs was linked with a more than a two-fold increased risk of small artery occlusion ischaemic stroke while high consumption of ASBs was associated with significantly increased risk of ischaemic stroke in women with body mass index of at least 30 kg/m2.
The authors said future studies are needed to replicate the findings.