- Intermediate/high radioactive iodine (RAI) dose is associated with improved successful ablation and excellent response rates compared with low dose in patients with low-risk differentiated thyroid cancer (DTC).
Why this matters
- The management of patients with low-risk DTC is controversial, and some prior studies have shown equivalent outcomes between low- and high-dose RAI.
- Patients who received intermediate-/high-dose RAI (1.85-3.7 GBq) had higher rates of successful ablation (67% vs 35%; P<.001 and excellent response vs p=".020)" compared with those who received low-dose rai gbq style="list-style-type:circle;">
- More patients in the low-dose group had an indeterminate response (64% vs 43%; P=.005).
- 277 patients with low-risk DTC who received total thyroidectomy and RAI (174 low dose; 103 intermediate-high dose) were analyzed for outcomes.
- Funding: None disclosed.
- Retrospective study.