Direction of shunt in CHD affects uptake of anesthesia
Access to the full content of this site is available only to registered healthcare professionals.
Register to read more
In patients with congenital heart disease (CHD) with right-to-left shunt, the time to inhalational induction of anesthesia is significantly extended compared with patients without CHD or those with left-to-right shunt, in whom it is similar.
Sevoflurane is safe and maintains stable hemodynamics in the presence of CHD.
A prospective, single‑center clinical study.
93 pediatric patients undergoing elective surgery were segregated into 3 equal groups: group 1 (no CHD), group 2 (acyanotic CHD) and group 3 (cyanotic CHD).
General anesthesia was induced with 8% sevoflurane in 6 L/min air‑oxygen.
Time to induction was noted at loss of eyelash reflex and decrease in bispectral index (BIS) value below 60.
End-tidal sevoflurane concentration, minimum alveolar concentration, and BIS were recorded at 15 s intervals for the first min, followed by 30 s interval for another 1 min during induction.
Hemodynamic data were recorded before and after induction.