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Clinical Summary

Does depression influence physical activity levels in patients with CVD risk?

Takeaway

  • Patients at high-risk for cardiovascular disease (CVD) with depressive symptoms may have lower physical activity levels, with a moderate association between depressive symptoms and daily step count.
  • Interventions should be targeted to individuals with lowest activity rating, those with higher BMIs, or current smokers.

Why this matters

  • Physical activity, if followed as per WHO recommendations, can reduce global CVD risk by 6%.
  • There is limited data pertaining to the relationship between depressive symptoms and step count.

Study design

  • Cross-sectional study of 1742 adults from 135 primary care practices in South London with high risk for developing CVD in the next 10 years.
  • Patients were assessed for CVD risk using QRISK2 score and for depression using Patient Health Questionnaire-9.
  • Funding: National Institute for Health Research - Health Technology Assessment Programme.

Key results

  • Overall, daily step count was between 105 to 21,313 steps.
  • After adjustments, participants with moderate to severe depressive symptoms were found to walk 15.6% less (P=.001) and those with mild depressive symptoms were found to walk 13.5% less (P<.001) than participants without depression.
  • Every 1-year increase in age and a 1-point increase in BMI was associated with a decrease in step count by 1.2% in patients with moderate to severe depressive symptoms (P<.001) and by 2.7% in those with mild depressive symptoms (P<.001).
  • Current smokers’ step count was 19.1% lower than that of non-smokers (P<.001).

Limitations

  • Cross-sectional study design.

References


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