- Among women trying to conceive, reduced sleep hours and night-shift work are not clearly associated with decreased fecundability (conceiving within a single cycle).
- Subjective report of trouble sleeping at night more often than not was tied to reduced fecundability.
Why this matters
- Suboptimal sleep has been associated with increased risks for heart disease, obesity, diabetes, and all-cause mortality.
- In the U.S., 12% of employed women participate in night-shift work.
- Trouble sleeping was positively associated with elevated BMI, depression diagnosis, Perceived Stress Scale (PSS-10) score, and tobacco use.
- Trouble sleeping was inversely associated with income, education, and sleep duration.
- Women who had "trouble sleeping at night" >50% of time had reduced fecundability:
- adjusted fecundability ratio, 0.73 (95% CI, 0.60-0.89).
- Data showed that a small reduced fecundability with short sleep and shift work was not statistically significant.
- Prospective cohort study.
- Cohort taken from the Pregnancy Study Online (PRESTO), an ongoing web-based preconception cohort study of North American pregnancy planners (n=6873).
- Questionnaires used to assess sleep habits and time to pregnancy.
- Funding: Eunice Kennedy Shriver National Institute of Child Health and Human Development.
- Quantity and quality of sleep are subject to recall bias and misclassification.