- Adjuvant lifestyle interventions improve outcomes over medication alone in gastroesophageal reflux disease (GERD).
Why this matters
- Poor habits such as rapid eating, consumption beyond fullness, and intake of very hot foods can worsen GERD and reduce treatment efficacy.
- Researchers surveyed patients with and without GERD from 6 hospitals (N=1518; 832 with GERD, 686 without GERD) to explore associations among symptoms, clinical characteristics, and lifestyle factors.
- Funding: National Key Research and Development Program of China; National Natural Science Foundation of China; Central South University of China.
- Logistic multivariate regression analysis showed these GERD risk factors:
- Fast eating (OR, 4.06).
- Eating beyond fullness (OR, 2.85).
- Wearing girdles or corsets (OR, 2.19).
- Eating very hot foods (OR, 1.81).
- High BMI (OR, 1.81).
- Lying down soon after eating (OR, 1.54).
- Smoking (OR, 1.52).
- Mann-Whitney rank sum testing showed lifestyle interventions in addition to medication improved 6-month outcomes over medication alone (U=35276.000; Z=−8.578; P<.001>
- Patient symptoms and lifestyle factors were self-reported.